Multiple Cranial Neuropathies and Pachymeningitis in a Patient With a Pathogenic Nucleotide-Binding Oligomerization Domain 2 Polymorphism

Sravanthi Vegunta, MD, John Bohnsack, MD, Alison Crum, MD, Kathleen Digre, MD, Bradley Katz, MD, PhD, Meagan Seay, DO, Edward Quigley, MD, PhD, Sean Kennedy, MD, Nick Mamalis, MD, Judith Warner, MD

Multiple Cranial Neuropathies and Pachymeningitis in a Patient With a Pathogenic Nucleotide-Binding Oligomerization Domain 2 Polymorphism

Authors: MD, John Bohnsack, MD, Alison Crum, MD, Kathleen Digre, MD, Bradley Katz, MD, PhD, Meagan Seay, DO, Edward Quigley, MD, PhD, Sean Kennedy, MD, Nick Mamalis, MD, Judith Warner, MD Sravanthi Vegunta
Publication date: 1 December 2021
Publisher: Lippincott, Williams & Wilkins

Abstract

An 11-year-old boy presented with 2 weeks of intermittent headache, right orbital pain, and constant diplopia. Brain MRI showed dural thickening and enhancement of the right lateral cavernous sinus, right orbital apex, and tentorium. Initial cerebral spinal fluid analysis showed only mild pleocytosis, and serum diagnostics were unrevealing

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