CLINICO-DEMOGRAPHIC STUDY OF PATIENTS WITH ACANTHOSIS NIGRICANS- A MENACE FOR CARDIO-VASCULAR DISEASE: Clinico-Demographic Study Of Acanthosis Nigricans

Abstract

ABSTRACT:-  INTRODUCTION-  Acanthosis  Nigricans (AN) is characterized by dark, coarse and thickened skin with a velvety texture, involving  the neck, the axillae, flexor of large joints significant association  of Coronary  Heart disease in patients of Acanthosis Nigricans was noticed. AIM -We have done this to study the prevalence, clinico-demographic and etiological profile of patients presenting with AN and   to draw relations if any, with CardioVascular Disease(CVD) MATERIALS AND METHODS-  It was an observational, descriptive, institution based cross-sectional study and was conducted  at  the out  patient  department   (OPD) of Dermatology, Venereology and Leprosy of A tertiary care hospital in Eastern part of India, An attempt was made to detect etiological factor of the disease by noting the temporal association between the disease and any systemic associations with special attention to CVD. RESULTS-  High  BMI was seen  in 71.9% cases , Systolic hypertension in 35.3% , Diastolic hypertension in 43.9% , raised Fasting Blood Sugar in 30.2% and raised PP Sugar in 15.8% patients .  Significant relation seen between High BMI, raised Cholesterol, Triglycerides ,and PPBS with Systolic And Diastolic Hypertension. CONCLUSION – In  AN patients who have high BMI have the highest chance of developing CVD, as also Hypercholesterolemia and Hyper tryglyceridemia. Raised fasting blood sugar noted additional factor for developing diastolic hypertension