CLINICO-DEMOGRAPHIC STUDY OF PATIENTS WITH ACANTHOSIS NIGRICANS- A MENACE FOR CARDIO-VASCULAR DISEASE: Clinico-Demographic Study Of Acanthosis Nigricans
ABSTRACT:-
INTRODUCTION- Acanthosis Nigricans (AN) is characterized by dark, coarse and thickened skin with a velvety texture, involving the neck, the axillae, flexor of large joints significant association of Coronary Heart disease in patients of Acanthosis Nigricans was noticed.
AIM -We have done this to study the prevalence, clinico-demographic and etiological profile of patients presenting with AN and to draw relations if any, with CardioVascular Disease(CVD)
MATERIALS AND METHODS- It was an observational, descriptive, institution based cross-sectional study and was conducted at the out patient department (OPD) of Dermatology, Venereology and Leprosy of A tertiary care hospital in Eastern part of India,
An attempt was made to detect etiological factor of the disease by noting the temporal association between the disease and any systemic associations with special attention to CVD.
RESULTS- High BMI was seen in 71.9% cases , Systolic hypertension in 35.3% , Diastolic hypertension in 43.9% , raised Fasting Blood Sugar in 30.2% and raised PP Sugar in 15.8% patients . Significant relation seen between High BMI, raised Cholesterol, Triglycerides ,and PPBS with Systolic And Diastolic Hypertension.
CONCLUSION – In AN patients who have high BMI have the highest chance of developing CVD, as also Hypercholesterolemia and Hyper tryglyceridemia. Raised fasting blood sugar noted additional factor for developing diastolic hypertension