Shigellosis is a disease of public health importance in developing
countries. It may cause self-limited diarrhea to severe dysentery.
Emergence of multi drug resistant (MDR) strains is a growing concern
globally. Ceftriaxone and ciprofloxacin are the drugs of choice for MDR
cases. Here, we report a case of MDR Shigella flexnerifrom an
immunocompromised patient. The strain was resistant to ceftriaxone
[minimum inhibitory concentration (MIC) ≥ 64 μg/ml],
limiting the treatment option. Simultaneously, the strain was also
found to be resistant to ciprofloxacin (MIC ≥ 4 μg/ml).
However, it was susceptible to ceftazidime (MIC 4 μg/ml). This is
the first case of ceftriaxone resistant Shigella spp. reported from our
hospital
