In this paper, we develop a novel efficient and robust nonparametric
regression estimator under a framework of feedforward neural network. There are
several interesting characteristics for the proposed estimator. First, the loss
function is built upon an estimated maximum likelihood function, who integrates
the information from observed data, as well as the information from data
structure. Consequently, the resulting estimator has desirable optimal
properties, such as efficiency. Second, different from the traditional maximum
likelihood estimation (MLE), the proposed method avoid the specification of the
distribution, hence is flexible to any kind of distribution, such as heavy
tails, multimodal or heterogeneous distribution. Third, the proposed loss
function relies on probabilities rather than direct observations as in least
squares, contributing the robustness in the proposed estimator. Finally, the
proposed loss function involves nonparametric regression function only. This
enables a direct application of existing packages, simplifying the computation
and programming. We establish the large sample property of the proposed
estimator in terms of its excess risk and minimax near-optimal rate. The
theoretical results demonstrate that the proposed estimator is equivalent to
the true MLE in which the density function is known. Our simulation studies
show that the proposed estimator outperforms the existing methods in terms of
prediction accuracy, efficiency and robustness. Particularly, it is comparable
to the true MLE, and even gets better as the sample size increases. This
implies that the adaptive and data-driven loss function from the estimated
density may offer an additional avenue for capturing valuable information. We
further apply the proposed method to four real data examples, resulting in
significantly reduced out-of-sample prediction errors compared to existing
methods