International Journal of Exercise Science 16(2): 676-687, 2023. The study aimed to assess cardiovascular responses to low-intensity aerobic exercise with varying levels of limb occlusion pressures (LOP) in a healthy population of men and women 30 to 60 years. The study was a single-session repeated measures design. Thirty individuals completed the study. All subjects participated in a single bout of low-intensity cycling (30-39% HRR) with bilateral lower extremity (LE) BFR for four 5-minute stages [0% (No BFR), 40%, 60%, and 80% LOP] with a 2-minute active rest between stages (BFR pressure released). The subjects’ systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR), oxygen saturation (SpO2), and ratings of perceived exertion (RPE) were measured at rest, peak, immediately post, post-15 minutes, and post-30 minutes. Peak SBP (no BFR 160.7 ±19.1 mmHg; 40% LOP 173.6 ± 18.7 mmHg; 60 % LOP; 182.5 ± 21.1 mmHg; 80% LOP 193.5± 23.3 mmHg ; p\u3c0.001; =.747), DBP (no BFR 74.9 ± 8.5 mmHg; 40% LOP (83.0 ± 9.0 mmHg;60 % LOP 90.4 ± 8.7 mmHg; 80% LOP 97.7 ± 9.5 mmHg ;p\u3c0.001; =.924), MAP (no BFR 103.5 ± 10.1 mmHg; 40% LOP 113.2 ± 10.5 mmHg; 60% LOP 121.1 ± 11.7 mmHg; 80% LOP 129.7 ± 12.9 mmHg; p\u3c0.001; =.960), and RPE (No BFR 10.0 ± 2.0; 40 % LOP 11.5 ± 2.3; 60% LOP 13.2 ± 2.6; 80% LOP 14.5 ± 3.; p\u3c0.001; =.826) were significantly higher with each progressing stage. The results indicate that low-intensity cycling with bilateral LE BFR for each LOP stage resulted in elevated SBP, DBP, MAP, and RPE despite maintaining a fixed HR
