The article contains the results of long-term research of geochemical features of nickel in oils from 36 deposits of the main oil and gas region of Ukraine - the DniproDonetsk basin. The results of correlation and regression analyzes revealed the character and forms of the relationship between the nickel content in oils and vanadium; zinc; chromium; the total content of V, Zn, Cr, Mn, Co, Fe, Hg, Al; average thickness of the productive horizon; oil density values; oil viscosity values; resin content; formation water density from the productive horizon; sulfur content in oil; manganese; cobalt; metal; mercury; aluminum; the current depth of the productive horizon; modern temperature of the productive horizon; modern pressure in the productive horizon; oil initial boiling point temperature; the content of paraffins; salinity values of formation water from the productive horizon; content of asphaltenes. The calculated correlation coefficients, linear pair regression equations and their graphs between these parameters are given. Based on the results of cluster analysis, a dendrogram of the results of clustering by the weighted centroid method of deposits on the nickel content in the oils of the considered deposits was constructed