CORE
🇺🇦
make metadata, not war
Services
Services overview
Explore all CORE services
Access to raw data
API
Dataset
FastSync
Content discovery
Recommender
Discovery
OAI identifiers
OAI Resolver
Managing content
Dashboard
Bespoke contracts
Consultancy services
Support us
Support us
Membership
Sponsorship
Community governance
Advisory Board
Board of supporters
Research network
About
About us
Our mission
Team
Blog
FAQs
Contact us
Brachypodium distachyon as a model for defining the allergen potential of non-prolamin proteins
Authors
E Balázs
G Gell
+4 more
R Haraszi
A Juhász
E Sebestyén
L Tamás
Publication date
1 January 2012
Publisher
Doi
Cite
View
on
PubMed
Abstract
Epitope databases and the protein sequences of published plant genomes are suitable to identify some of the proteins causing food allergies and sensitivities. Brachypodium distachyon, a diploid wild grass with a sequenced genome and low prolamin content, is the closest relative of the allergen cereals, such as wheat or barley. Using the Brachypodium genome sequence, a workflow has been developed to identify potentially harmful proteins which may cause either celiac disease or wheat allergy-related symptoms. Seed tissue-specific expression of the potential allergens has been determined, and intact epitopes following an in silico digestion with several endopeptidases have been identified. Molecular function of allergen proteins has been evaluated using Gene Ontology terms. Biologically overrepresented proteins and potentially allergen protein families have been identified. © 2012 The Author(s)
Similar works
Full text
Open in the Core reader
Download PDF
Available Versions
Springer - Publisher Connector
See this paper in CORE
Go to the repository landing page
Download from data provider
Last time updated on 05/06/2019
ELTE Digital Institutional Repository (EDIT)
See this paper in CORE
Go to the repository landing page
Download from data provider
oai:edit.elte.hu:10831/91251
Last time updated on 13/09/2023