The diseases pathologically manifested with endothelial cell hyperplasia can present with multiple clinical manifestations， which correspond to different types of clinical diseases. Comprehensive analysis of clinical characteristics of the patients combined with light microscopy， immunofluorescence and electron microscopy can make the corresponding diagnosis. Early and accurate diagnosis is of significance for the treatment， prognosis and management of renal diseases. In this article， renal diseases pathologically manifested with endothelial cell hyperplasia were illustrated， and the diagnostic thinking was briefly summarized
