To improve the accuracy of the calculation for the current mineral resource reserves, a calculation method for mineral resource reserves based on multi-point geostatistics was proposed. The new method, including four major steps, focuses on calculating resource reserves of ore body accurately for rational development and utilization of mineral resources. To represent the spatial geometric relationship of the ore body accurately, a three-dimensional irregular tetrahedron voxel (3D ITV) model construction method for the ore body is proposed first. Second, a tetrahedron voxel grade model built by the mineral reservation calculation oriented multi-point geostatistics method is proposed. The construction of 3D training image, definition of data template with N-order adjacency voxels, construction of search trees and conditional probability extraction of data event are conducted in this step. Finally, the resource reserves of the ore body are calculated on the basis of the tetrahedron voxel grade model. A calculation experiment of copper reserves is conducted to demonstrate the validity of the new method. The new method can be meaningful to the exploration, development, and utilization of mineral
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