Universidad de Murcia. Departamento de Biología Celular e Histología
Abstract
Recently developed RNA microarrays and
high-throughput sequencing techniques have
demonstrated that long non-coding RNAs (lncRNAs)
play important roles in a wide range of biological
processes. Emerging evidence has confirmed the
relevance of lncRNAs to diverse types of human disease,
including cancer and cardiovascular disease. In this
review, we discuss the important functions of lncRNAs
in respiratory diseases. Because the reviewed studies
have mainly focused on non-small cell lung cancer,
future work will need to extend the studies into other
respiratory diseases. From a clinical perspective,
targeting lncRNAs as a novel therapeutic strategy in
respiratory diseases will require further study to further
clarify their biological functions