F. Hernández y Juan F. Madrid. Universidad de Murcia: Departamento de Biología Celular e Histología
Abstract
The population of the world grows every
year, and life expectancy tends to increase. Thus, longterm
preservation of teeth in aged individuals is an
urgent issue. The main causes of tooth loss are well
known to be periodontitis, caries, fractures, and
orthodontic conditions. Although implant placement is a
widely accepted treatment for tooth loss, most patients
desire to preserve their own teeth. Many clinicians and
researchers are therefore challenged to treat and preserve
teeth that are irreversibly affected by deep caries,
periodontitis, fractures, and trauma. Tissue engineering
techniques are beneficial in addressing this issue; stem
cells, signal molecules, and scaffolds are the main
elements of such techniques. In this review, we describe
these three elements with respect to their validation for
regeneration of the periodontium and focus particularly
on the potency of diverse scaffolds. In addition, we
provide a short overview of the ongoing studies of 4-
methacryloxyethyl trimellitate anhydride/methyl
methacrylate-tri-n-butyl-borane resin including calcium
chloride or hydroxyapatite for periodontium
regeneration