This study aims to know the level of understanding of UNM student’s experiencing misconceptions, understand the concept and do not understand the concept about cell biology using Two-Tier MCQs method. This research includes descriptive research. In this study, the Two-Tier MCQs method to identify student’s misconceptions. Population in this research is all student of study program of biology of UNM class 2015. Samples in this research as many as 20 people who tried randomly. Instruments used to test Two-Tier MCQs and interview methods to determine the causes of misconceptions. The result of data analysis shows that the highest misconception is in the mate rial structure and function of mitochondria and the lowest is in the cell cycle materia
