Additional file 1: Fig. S1. Catalog of localized mutational processes and their mutation rates. Fig. S2. Catalog of sequence dependencies. Fig. S3. Cosine similarities between signatures. Fig. S4. Mutation rates of 11-mers with and without hotspots. Fig. S5. Background 11-mer sets derived from mutational signatures. Fig. S6. UV-signature sequence characteristics across mutation rates. Fig. S7. Characterization of GAAACTTCTTT-sequences in repetitive elements. Table S1. K-mer statistics