Like all students with special needs, those with ASD are unique. To help them develop their skills and capacities, they need specialized programs and interventions. The main purpose of this study was to understand teachers’ knowledge about sight words intervention. In addition to that, the study was intended to discover teachers’ perspectives on the use of sight words to enhance reading skills of Saudi students with ASD. 89 male and female teachers of students with ASD participated in this study. The result showed that teachers have a high level of knowledge about sight word strategy in teaching reading to their students with ASD. In addition, teachers see that the use of sight words is moderately effective in enhancing on other aspect of literacy of students with ASD