Evaluation the Electrocardiography Changes in Patient with Perforated Peptic Ulcer (PPU) Underwent Surgery in Firouzabadi Hospital

Abstract

Background & Aims:  Although Peptic ulcer is a benign lesion of the gastrointestinal tract often caused by the secretion of gastric acid and/or the multiplication of Helicobacter pylori, but its rupture (perforated peptic ulcer (PPU)) is a surgical emergency and requires immediate action. PPU could cause ECG changes leading to masking the patient's main disease and wrong treatment. In this study we evaluated the prevalence of changes in the ECG of patients with perforated peptic ulcer in Firouzabadi Hospital. Materials and Methods: In this cross-sectional study, demographic data of all patients with PPU in Firouzabadi Hospital were extracted from the archives and electrographs were earned by cardiologists and internal medicine specialists while visiting. Statistical analyses were fulfilled by SPSS V.22 software with significance level of 0.05. Results: 119 patients (86 males and 33 females) with PPU with mean age of 48.99 ± 16.18 were included in this study. Among 66 patients (55.5%) with band changes, 41 patients had one, 16 had two, 4 had three, and 5 had four pathological changes in their ECG. The most common pathological finding was T wave inversion which was observed in 29 patients (24.5%). more in male patients. There was no significant relationship between ECG findings with factors likeage, smoking, alcohol consumption, and a history of diseases such as diabetes, hypertension, and ischemic heart disease (P> 0.05). Conclusion: More than half of patients with PPU have at least one preoperative electrocardiographic change. Gender is an influential factor in PPU and electrocardiographic changes. Although the frequency of these changes was more common among populations with hypertension, diabetes, and ischemic vascular disease, but there was no statistically connections between them