Introduction: Benign nontoxic multinodular goiter is one of the most common endocrine diseases and there is no consensus on the ideal treatment. The options should be evaluated individually, for each patient, taking into account factors such as risk-benefit ratio, patient preference and experience of the treating physician.
Objective: To update the knowledge of therapeutic options for patients with benign nontoxic multinodular goiter.
Development: The current alternatives for treatment are: clinical follow-up for asymptomatic patients; suppressive therapy with levothyroxine; therapy with radioactive iodine alone or preceded by recombinant human TSH and surgical intervention. Other authors include within these alternatives, minimally invasive techniques.
Conclusions: Surgical intervention is the fundamental option for the treatment of the symptomatic patient. Minimally invasive procedures show good results in improving quality of life and patient satisfaction. More long-term follow-up studies of these patients are required
