We report a 23% asymptomatic severe acute respiratory syndrome
coronavirus 2 (SARS CoV-2) Omicron carriage rate in
participants being enrolled into a clinical trial in South Africa,
15-fold higher than in trials before Omicron. We also found
lower CD4 + T-cell counts in persons with human immunodeficiency
virus (HIV) strongly correlated with increased odds of
being SARS-CoV-2 polymerase chain reaction (PCR) positive.The National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) grants. The Sisonke study was funded by the National Treasury of South Africa; the National Department of Health; Solidarity Response Fund NPC; The Michael & Susan Dell Foundation; The Elma Vaccines and Immunization Foundation; and the Bill & Melinda Gates Foundation.https://academic.oup.com/cidam2023Paediatrics and Child Healt
