BackgroundWith rising United States health care expenditure, estimating current spending for patients with heart failure (HF) informs the value of preventative health interventions.ObjectivesThe purpose of this study was to estimate current health care expenditure growth for patients with HF in the United States.MethodsThe authors pooled MEPS (Medical Expenditure Panel Survey) data from 2009-2018 to calculate total HF-related expenditure across clinical settings in the United States. A 2-part model adjusted for demographics, comorbidities, and year was used to estimate annual mean and incremental expenditures associated with HF.ResultsIn the United States, an average of 28,950(2018inflationβadjusteddollars)isspentperyearforhealthcareβrelatedexpenditureforindividualswithHFcomparedwith5,727 for individuals without HF. After adjusting for demographics and comorbidities, a diagnosis of HF was associated with 3,594inannualincrementalexpenditurecomparedwiththosewithoutHF.HFβrelatedexpenditureincreasedfrom26,864 annual per person in 2009-2010 to 32,955in2017β2018,representinga2312,569 per year. Outpatient office-based care and prescription medications saw the greatest growth in cost over the period, 41% and 24%, respectively. Estimated incremental national expenditure for HF per year was 22.3billion;totalannualexpenditureforadultswithHFwas179.5 billion.ConclusionsHF is a costly condition for which expenditure is growing faster than that of other chronic conditions