Hirakoba, Kohji

This study was designed to theoretically reexamine the validity in noninvasive prediction of blood lactate (La) accumulation from excess CO2 output (CO2 excess) generated during exercise based on the data obtained in a previous study of Hirakoba et al. (12). Several assumptions were made; 1) total body water (TBW) corresponds to 60% of body mass, 2) La and hydrogen ion (H+) are uniformly distributed in a whole TBW, 3) CO2 excess derives from bicarbonate buffering of H+ dissociated from lactic acid, and is equicalent to La accumulated in the body. From these assumptions, prediction of blood La accumulation (ΔLa,predicted) and distribution volume of La (VLa) were calculated from CO2 excess, TBW and actually measured blood La accumulation (ΔLa,measured) during a three stages of constant work rate exercise test. The ΔLa,predicted was found to be significantly lower than ΔLa,measured was 21.4±5.3 l, which means that an average percent of VLa to TBW (%VLa) was 61.9±11.6%. Namely, it was found that the VLa obtained in this study was not equal to the TBW and %VLa was different among subjects. Therefore, the data indicate that noninvasive prediction error of blood La accumulation from CO2 excess during exercise would be accounted in part for by individuals' VLa during exercise test used in this study

Validity in Noninvasive Prediction of Blood Lactate Accumulation from Excess CO2 Output During Exercise

Abstract

Similar works

Full text

Available Versions

Institutional Repositories DataBase (IRDB)