AIM: The masseter muscle is often exploited by craniofacial surgeons in transposition operations to correct facial palsy, benign masseteric hypertrophy; or neurectomy-induced atrophy of the muscle. A clear understanding of the course of the premasseteric branch of the facial artery and its relations with adjacent structures is essential in maneuvering the masseter muscle safely. In the present study the premasseteric branch was analyzed in details