The hardware computing landscape is changing. What used to be distributed
systems can now be found on a chip with highly configurable, diverse,
specialized and general purpose units. Such Systems-on-a-Chip (SoC) are used to
control today's cyber-physical systems, being the building blocks of critical
infrastructures. They are deployed in harsh environments and are connected to
the cyberspace, which makes them exposed to both accidental faults and targeted
cyberattacks. This is in addition to the changing fault landscape that
continued technology scaling, emerging devices and novel application scenarios
will bring. In this paper, we discuss how the very features, distributed,
parallelized, reconfigurable, heterogeneous, that cause many of the imminent
and emerging security and resilience challenges, also open avenues for their
cure though SoC replication, diversity, rejuvenation, adaptation, and
hybridization. We show how to leverage these techniques at different levels
across the entire SoC hardware/software stack, calling for more research on the
topic