Please view abstract in the attached PDF file

Fehling, P.

Heffernan, K

Hultquist, E.

Lefferts, W.

Smith, D.

TopSCHOLAR

VASCULAR CHANGES FOLLOWING EXERCISE-INDUCED HYPERTHERMIA     Lefferts, W.1, Hultquist, E.2, Heffernan, K.1, Fehling, P.2, Smith, D.2 1Syracuse University, Syracuse, NY, 2Skidmore College, Saratoga Springs, NY  wleffert@syr.edu, ehultqui@skidmore.edu, ksheffer@syr.edu, pfehling@skidmore.edu, dsmith@skidmore.edu  The combination of hyperthermia and heavy exercise/exertion encountered during firefighting may impair vascular function, increasing risk of sudden cardiac events. Purpose: To isolate the effect of exercise-induced hyperthermia on arterial stiffness and coronary perfusion. Methods: Vascular measures were collected in 12 healthy men (age 22 ± 3yr; BMI 24.6 ± 2.8kg·m-2; VO2max 60.3 ± 4.44mL·kg-1·min-1) pre and post 100-minutes of intermittent exercise (3 bouts) in 2 randomized conditions: hyperthermic (HYT; wearing personal protective equipment), and normothermic (NOT; wearing a cooling shirt and weight equivalent to PPE). Results: Hyperthermic mean core temperature was significantly higher than NOT during the third exercise bout (peak 37.82 ± 0.22 vs 37.21 ± 0.40 °C) and into recovery (p<0.05). Measures related to coronary perfusion (subendocardial viability ratio, backwards wave pressure) were significantly lower for HYT-Post compared to other times/conditions (Table 1; p<0.05). No significant changes were found in arterial stiffness (forward wave pressure or pulse wave velocity). Conclusion: Exercise-induced hyperthermia reduces indices of coronary perfusion without affecting arterial stiffness. Table 1: Vascular and hemodynamic variables pre and post exercise (mean ± SE; N=12)   NOT-Pre NOT-Post HYT-Pre HYT-Post Subendocardial viability ratio 208 ± 9 232 ± 13 200 ± 9   150 ± 11* Forward pressure wave (mmHg)   33 ± 2 33 ± 2  33 ± 2 33 ± 2 Backwards pressure wave (mmHg)   16 ± 1   16 ± 11   16 ± 11   11 ± 1* Pulse wave velocity (m·s-1)     4.9 ± 0.1   4.9 ± 0.2   5.0 ± 0.1   4.9 ± 0.1 * HYT-Post < NOT-Pre, NOT-Post, HYT-Pre (p<0.05)    Supported by FEMA Assistance to Firefighters Grant program EMW-2010-FP-01992  

Vascular Changes Following Exercise-Induced Hyperthermia

http://digitalcommons.wku.edu/cgi/viewcontent.cgi?article=1713&context=ijesab

Vascular Changes Following Exercise-Induced Hyperthermia

Abstract

Similar works

Full text

Available Versions

TopSCHOLAR