Introduction: The mouth, jaw, and face are prone to oral and maxillofacial tumors, constituting a significant proportion of pathological lesions in Iran. Therefore, the present study aimed to investigate the frequency of oral and maxillofacial tumors in the samples referred to the Pathology Department of Qazvin University of Medical Sciences.Materials and Methods: This cross-sectional descriptive study was performed on 110 patients referred to Qazvin Dental Clinic with pathological diagnosis of oral and maxillofacial tumors. After reviewing the medical files, information on tumor type, anatomical location, tissue origin, age range, gender, smoking and drug use, alcohol consumption, family history, and pathological diagnosis were extracted. The data were analyzed in SPSS software (version 25).Results: According to the findings of the study, 58.18% of women and 41.81% of men developed tumors of the mouth, jaw, and face. These pathological lesions were in the age range of 9-90 years (mean age of 41.04±20.29 years). They made up 42.72% of benign tumors and 57.27% of malignant ones. Among these, 84 cases were odontogenic tumors, and 26 cases were non-odontogenic tumors.Conclusion: As evidenced by the obtained results, oral squamous cell carcinoma was the most common among Oral and Maxillofacial tumors. This finding is consistent with the results of many epidemiological studies in the field of tumors of the mouth, jaw, and face
