Multiplexed Assays of Variant Effect (MAVEs) have emerged as a powerful
approach for interrogating thousands of genetic variants in a single
experiment. The flexibility and widespread adoption of these techniques across
diverse disciplines has led to a heterogeneous mix of data formats and
descriptions, which complicates the downstream use of the resulting datasets.
To address these issues and promote reproducibility and reuse of MAVE data, we
define a set of minimum information standards for MAVE data and metadata and
outline a controlled vocabulary aligned with established biomedical ontologies
for describing these experimental designs