Appelman, Y

Baak, R

Beishuizen, A

Blans, MJ

Bleeker, GB

Bosker, HA

Camaro, C

Crijns, H

de Ruijter, W

Delnoij, TSR

Dubois, Eric

Eikemans, BJW

Elbers, PW

Gosselink, MTM

Heestermans, T

Henriques, JP

Janssens, GN

Jessurun, G A J

Jewbali, Lucia

Lemkes, JS

Magro, M

Meuwissen, M

Oemrawsingh, PV

Plomp, K

Rijpstra, TA

Royen, N

Spoormans, EM

Stoel, M

van de Ven, PM

van den Bogaard, B

van der Harst, P

van der Heijden, JJ

van der Hoeven, H

van der Hoeven, NW

van der Horst, ICC

Vink, MA

Vlaar, APJ

Vlachojannis, GJ

Voskuil, M

English

EUR Research Repository

EUR Research Information PortalData on sex differences in one-year outcomes of out-of-hospital cardiac arrest patientswithout ST-segment elevationPublished in:Data in BriefPublication status and date:Published: 01/01/2020DOI (link to publisher):10.1016/j.dib.2020.106521Document VersionPublisher's PDF, also known as Version of recordCitation for the published version (APA):Spoormans, EM., Lemkes, JS., Janssens, GN., van der Hoeven, NW., Jewbali, L., Dubois, E., van de Ven, PM., Meuwissen,M., Rijpstra, TA., Bosker, HA., Blans, MJ., Bleeker, GB., Baak, R., Vlachojannis, GJ., Eikemans, BJW., van der Harst, P.,van der Horst, ICC., Voskuil, M., van der Heijden, JJ., ... Royen, N. (2020). Data on sex differences in one-year outcomes ofout-of-hospital cardiac arrest patients without ST-segment elevation. Data in Brief, 33, Article 106521.https://doi.org/10.1016/j.dib.2020.106521Link to publication on the EUR Research Information PortalTerms and Conditions of UseExcept as permitted by the applicable copyright law, you may not reproduce or make this material available to any third partywithout the prior written permission from the copyright holder(s). Copyright law allows the following uses of this materialwithout prior permission:            • you may download, save and print a copy of this material for your personal use only;            • you may share the EUR portal link to this material.In case the material is published with an open access license (e.g. a Creative Commons (CC) license), other uses may beallowed. Please check the terms and conditions of the specific license.Take-down policyIf you believe that this material infringes your copyright and/or any other intellectual property rights, you may request itsremoval by contacting us at the following email address: openaccess.library@eur.nl. Please provide us with all the relevantinformation, including the reasons why you believe any of your rights have been infringed. In case of a legitimate complaint,we will make the material inaccessible and/or remove it from the website.Data in Brief 33 (2020) 106521 Contents lists available at ScienceDirect Data in Brief journal homepage: www.elsevier.com/locate/dib Data Article Data on sex differences in one-year outcomes of out-of-hospital cardiac arrest patients without ST-segment elevation Eva M. Spoormans a , Jorrit S. Lemkes a , ∗, Gladys N. Janssens a , Nina W. van der Hoeven a , Lucia S.D. Jewbali b , Eric A. Dubois b , Peter M. van de Ven c , Martijn Meuwissen d , Tom A. Rijpstra e , Hans A. Bosker f , Michiel J. Blans g , Gabe B. Bleeker h , Remon Baak i , Georgios J. Vlachojannis j , n , Bob J.W. Eikemans k , Pim van der Harst l , p , Iwan C.C. van der Horst m , z , Michiel Voskuil n , Joris J. van der Heijden o , Albertus Beishuizen p , Martin Stoel q , Cyril Camaro r , Hans van der Hoeven s , José P. Henriques t , Alexander P.J. Vlaar u , Maarten A. Vink v , Bas van den Bogaard w , Ton A.C.M. Heestermans x , Wouter de Ruijter y , Thijs S.R. Delnoij z , Harry J.G.M. Crijns aa , Gillian A.J. Jessurun bb , Pranobe V. Oemrawsingh cc , Marcel T.M. Gosselink dd , Koos Plomp ee , Michael Magro ff, Paul W.G. Elbers gg , Yolande Appelman a , Niels van Royen a , r a Department of Cardiology, Amsterdam University Medical Center, location VUmc, Amsterdam, the Netherlands b Thorax Center, Erasmus Medical Center, Rotterdam, the Netherlands c Department of Epidemiology and Data Science, Amsterdam University Medical Center, location VUmc, Amsterdam, the Netherlands d Department of Cardiology, Amphia Hospital, Breda, the Netherlands e Department of Intensive care medicine, Amphia Hospital, Breda, the Netherlands f Department of Cardiology, Rijnstate Hospital, Arnhem, the Netherlands g Department of Intensive care medicine, Rijnstate Hospital, Arnhem, the Netherlands h Department of Cardiology, HAGA Hospital, Den Haag, the Netherlands i Department of Intensive care medicine, HAGA Hospital, Den Haag, the Netherlands j Department of Cardiology, Maasstad Hospital, Rotterdam, the Netherlands k Department of Intensive care medicine, Maasstad Hospital, Rotterdam, the Netherlands l University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, the Netherlands m University of Groningen, University Medical Center Groningen, Department of Intensive care medicine, Groningen, the Netherlands n Department of Cardiology, University Medical Center Utrecht, the Netherlands o Department of Intensive care medicine, University Medical Center Utrecht, the Netherlands p Department of Intensive care medicine, Medisch Spectrum Twente, Enschede, The Netherlands https://doi.org/10.1016/j.dib.2020.106521 2352-3409/© 2020 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license ( http://creativecommons.org/licenses/by-nc-nd/4.0/ ) 2 E.M. Spoormans, J.S. Lemkes and G.N. Janssens et al. / Data in Brief 33 (2020) 106521 q Department of Cardiology, Medisch Spectrum Twente, Enschede, The Netherlands r Department of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands s Department of Intensive care medicine, Radboud University Medical Center, Nijmegen, the Netherlands t Department of Cardiology, Amsterdam University Medical Center, location AMC, Amsterdam, the Netherlands u Department of Intensive care medicine, Amsterdam University Medical Center, location AMC, Amsterdam, the Netherlands v Department of Cardiology, OLVG, Amsterdam, the Netherlands w Department of Intensive care medicine, OLVG, Amsterdam, the Netherlands x Department of Cardiology, Noord West Ziekenhuisgroep, Alkmaar, the Netherlands y Department of Intensive care medicine, Noord West Ziekenhuisgroep, Alkmaar, the Netherlands z Department of Intensive care medicine, Maastricht University Medical Center, University Maastricht, Maastricht, the Netherlands aa Department of Cardiology, Maastricht University Medical Center, Maastricht, the Netherlands bb Department of Cardiology, Scheper Hospital, Emmen, the Netherlands cc Department of Cardiology, Haaglanden Medical Center, Den Haag, the Netherlands dd Department of Cardiology, Isala Hospital, Zwolle, the Netherlands ee Department of Cardiology, Tergooi Hospital, Blaricum, the Netherlands ff Department of Cardiology, Elisabeth-Tweesteden Hospital, Tilburg, the Netherlands gg Department of Intensive care medicine, Amsterdam University Medical Center, location VUmc, Amsterdam, the Netherlands a r t i c l e i n f o Article history: Received 27 October 2020 Accepted 9 November 2020 Available online 12 November 2020 Keywords: Sex differences Out-of-hospital cardiac arrest Coronary angiography One-year outcomes a b s t r a c t Sex differences in out-of-hospital cardiac arrest (OHCA) pa- tients are increasingly recognized. Although it has been found that post-resuscitated women are less likely to have significant coronary artery disease (CAD) than men, data on follow-up in these patients are limited. Data for this data in brief article was obtained as a part of the randomized controlled Coronary Angiography after Cardiac Arrest without ST-segment elevation (COACT) trial. The data supplements the manuscript “Sex differences in out-of-hospital cardiac ar- rest patients without ST-segment elevation: A COACT trial substudy” were it was found that women were less likely to have significant CAD including chronic total occlusions, and had worse survival when CAD was present. The dataset pre- sented in this paper describes sex differences on interven- tions, implantable-cardioverter defibrillator (ICD) shocks and hospitalizations due to heart failure during one-year follow- up in patients successfully resuscitated after OHCA. Data was derived through a telephone interview at one year with the patient or general practitioner. Patients in this randomized dataset reflects a homogenous study population, which can be valuable to further build on research regarding long-term sex differences and to further improve cardiac care. © 2020 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license ( http://creativecommons.org/licenses/by-nc-nd/4.0/ ) DOI of original article: 10.1016/j.resuscitation.2020.10.026 ∗ Corresponding author. E-mail address: j.lemkes@amsterdamumc.nl (J.S. Lemkes). E.M. Spoormans, J.S. Lemkes and G.N. Janssens et al. / Data in Brief 33 (2020) 106521 3 Specifications Table Subject Clinical Cardiology Specific subject area Out-of-hospital cardiac arrest without ST-segment elevation; sex differences in out-of-hospital cardiac arrest; one-year outcomes after cardiac arrest Type of data Table How data were acquired Data was obtained from the randomized-controlled Coronary Angiography after Cardiac Arrest without ST-segment elevation (COACT) trial [1] . Data format Raw and analysed Parameters for data collection Patients successfully resuscitated from OHCA, without ST-segment elevation, were included in the trial in the time period from January 2015 until July 2018. All patients that survived until one-year follow-up were included in this data in brief article. Description of data collection In the open-label multicentre COACT trial, which was performed in 19 hospitals in the Netherlands, patients successfully resuscitated after cardiac arrest without ST-segment elevation on the first post-resuscitation electrocardiogram were assigned to undergo immediate coronary angiography or delayed coronary angiography strategy until after neurological recovery [1] . All coronary angiography and PCI procedures were evaluated at an independent core laboratory by personnel who were unaware of the treatment assignments [1] . Follow-up data were obtained by a telephone interview with the patient [2] . Data source location Amsterdam UMC – location VUMC De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands Data accessibility Data are within this article. Related research article Eva M. Spoormans, Jorrit S. Lemkes, Gladys N. Janssens, Nina W. van der Hoeven, Lucia S.D. Jewbali, Eric A. Dubois, Peter M. van de Ven, Martijn Meuwissen, Tom A. Rijpstra, Hans A. Bosker, Michiel J. Blans, Gabe B. Bleeker, Remon Baak, Georgios J. Vlachojannis, Bob J.W. Eikemans, Pim van der Harst, Iwan C.C. van der Horst, Michiel Voskuil, Joris J. van der Heijden, Albertus Beishuizen, Martin Stoel, Cyril Camaro, Hans van der Hoeven, José P. Henriques, Alexander P.J. Vlaar, Maarten A. Vink, Bas van den Bogaard, Ton A.C.M. Heestermans, Wouter de Ruijter, Thijs S.R. Delnoij, Harry J.G.M. Crijns, Gillian A.J. Jessurun, Pranobe V. Oemrawsingh, Marcel T.M. Gosselink, Koos Plomp, Michael Magro, Paul W.G. Elbers, Yolande Appelman, Niels van Royen. Sex differences in patients with out-of-hospital cardiac arrest without ST-segment elevation: A COACT trial substudy. In Press Value of the Data • Sex differences in OHCA patients are increasingly recognized. Although it has been found that post-resuscitated women are less likely to have significant CAD than men, data on follow-up in these patients are limited. This data in brief article provides sex disparities on interven- tions and hospitalizations during one-year follow-up. • All patients in this randomized dataset were successfully resuscitated after OHCA with an initial shockable rhythm in absence of ST-segment elevation and therefore a reflects a ho- mogenous study population, which can be valuable to further build on research regarding long-term sex differences. • The data provide insights on how sex differences in coronary angiography findings and initial treatment strategy are related with long-term follow-up in men and women and can be used to further improve personalized cardiac care. 1. Data Description Data was obtained as a part of the randomized controlled Coronary Angiography after Car- diac Arrest without ST-segment elevation (COACT) trial. This data in brief article contains infor- mation on long-term follow-up in men and women ( Table 1 ). Analysis was performed according to intention-to-treat principle. Events from discharge to one-year follow-up were calculated as numbers and percentages of patients with odds ratios and 95% confidence intervals for dichoto- mous outcomes. Data was analyzed using IBM SPSS Statistics version 26 (IBM, Armonk, New York). 4 E.M. Spoormans, J.S. Lemkes and G.N. Janssens et al. / Data in Brief 33 (2020) 106521 Table 1 Interventions or hospitalization during one-year follow-up. Men ( N = 413) Women ( N = 109) Odds ratio 95% CI Coronary angiography — no. of patients. (%) 17/413 (4.1) 3/109 (2.8) 0.70 (0.19–2.29) Myocardial infarction — no. of patients. (%) 3/413 (0.7) 0/109 (0.0) a PCI — no. of patients. (%) 13/413 (3.1) 3/109 (2.8) 0.87 (0.24–3.11) CABG — no. of patients. (%) 3/413 (0.7) 1/109 (0.9) 1.27 (0.13–12.29) Hospitalization due to heart failure — no (%) 2/413 (0.5) 1/109 (0.9) 1.9 (0.17–21.18) ICD implantation — no. of patients. (%) 11/413 (2.7) 1/109 (0.9) 0.34 (0.04–2.64) ICD shocks — no. of patients. (%) 31/413 (7.5) 9/109 (8.3) 1.11 (0.51–2.41) Appropriate ICD shocks — no. of patients. (%) 27/413 (6.5) 4/109 (3.7) 0.12 (0.02–0.64) Composite of death, revascularization or myocardial infarction after index hospitalization — no. of patients. (%) 168/413 (40.7) 48/109 (44.0) 1.15 (0.75–1.76) All data are expressed in numbers and percentages (%). a OR and 95% not determined because of absence of events in women . PCI denotes percutaneous coronary interven- tion, CABG coronary artery bypass graft, ICD implantable cardioverter-defibrillator. 2. Experimental Design, Materials and Methods The investigator initiated, multicenter randomized controlled COACT trial investigated the benefit of immediate coronary angiography in patients successfully resuscitated after cardiac arrest without ST-segment elevation on the first post-resuscitation electrocardiogram [1] . Im- portant exclusion criteria were signs of ST-segment elevation, shock or an obvious non-coronary cause [1] . Further in- and exclusion criteria were reported previously [3] . Eligible patients for the study were randomized in a 1:1 ratio to either immediate coronary angiography (i.e. within two hours after randomization) or delayed coronary angiography strategy until after neurological recovery. In 19 participating hospitals in the Netherlands, a total of 552 patients were enrolled from January 2015 until July 2018. Post-resuscitation care was according to the resuscitation guidelines [4] . Fourteen patients retroactively withdrew informed consent. In addition, 13 pa- tients refused consent for the one-year follow-up and 3 patients were lost to follow-up. In total, 522 patients had data available for assessment at one year [2] . Data for the one-year follow-up included patients of whom follow-up was obtained and did not retract informed consent [2] . Death registries were searched to registry deaths. Follow-up data on interventions such as death, myocardial infarction, invasive coronary angiography or in- terventions, hospitalizations or implantable cardioverter defibrillator (ICD) therapy was obtained via an telephone interview with the patient, a family member or via patients’ the general physi- cian [2] . Information was obtained by members of the research team who were blinded for the patient’s treatment allocation. Ethics Statement Deferred informed consent was obtained from all patients that were enrolled in the study with the use of a prespecified procedure [1] . Declaration of Competing Interest Supported by unrestricted research grants from the Netherlands Heart Institute, Biotronik, and AstraZeneca. Dr. Vlachojannis reports receiving grant support from MicroPort Orthopedics and Daiichi Sankyo; and Dr. van Royen, receiving grant support from Philips, Biotronik, and Ab- bott and honoraria from Medtronic. No other potential conflict of interest relevant to this article was reported. E.M. Spoormans, J.S. Lemkes and G.N. Janssens et al. / Data in Brief 33 (2020) 106521 5 Supplementary Materials Supplementary material associated with this article can be found in the online version at doi: 10.1016/j.dib.2020.106521 . References [1] JS Lemkes , GN Janssens , NW van der Hoeven , LSD Jewbali , EA Dubois , M Meuwissen , et al. , Coronary angiography after cardiac arrest without ST-segment elevation, N. Engl. J. Med. 380 (15) (2019) 1397–1407 . [2] JS Lemkes , GN Janssens , NW van der Hoeven , LSD Jewbali , EA Dubois , MM Meuwissen , et al. , Coronary angiography after cardiac arrest without ST segment elevation: one-year outcomes of the COACT randomized clinical trial, JAMA Cardiol. (2020) . [3] JS Lemkes , GN Janssens , HM Straaten , PW Elbers , NW van der Hoeven , JG Tijssen , et al. , Coronary angiography after cardiac arrest: rationale and design of the COACT trial, Am. Heart J. 180 (2016) 39–45 . [4] JP Nolan , J Soar , A Cariou , T Cronberg , VR Moulaert , CD Deakin , et al. , European resuscitation council and European society of intensive care medicine 2015 guidelines for post-resuscitation care, Intensive Care Med. 41 (12) (2015) 2039–2056 . 

Data on sex differences in one-year outcomes of out-of-hospital cardiac arrest patients without ST-segment elevation

Data in Brief 33 (2020) 106521 Contents lists available at ScienceDirect Data in Brief journal homepage: www.elsevier.com/locate/dib Data Article Data on sex differences in one-year outcomes of out-of-hospital cardiac arrest patients without ST-segment elevation Eva M. Spoormans a , Jorrit S. Lemkes a , ∗, Gladys N. Janssens a , Nina W. van der Hoeven a , Lucia S.D. Jewbali b , Eric A. Dubois b , Peter M. van de Ven c , Martijn Meuwissen d , Tom A. Rijpstra e , Hans A. Bosker f , Michiel J. Blans g , Gabe B. Bleeker h , Remon Baak i , Georgios J. Vlachojannis j , n , Bob J.W. Eikemans k , Pim van der Harst l , p , Iwan C.C. van der Horst m , z , Michiel Voskuil n , Joris J. van der Heijden o , Albertus Beishuizen p , Martin Stoel q , Cyril Camaro r , Hans van der Hoeven s , José P. Henriques t , Alexander P.J. Vlaar u , Maarten A. Vink v , Bas van den Bogaard w , Ton A.C.M. Heestermans x , Wouter de Ruijter y , Thijs S.R. Delnoij z , Harry J.G.M. Crijns aa , Gillian A.J. Jessurun bb , Pranobe V. Oemrawsingh cc , Marcel T.M. Gosselink dd , Koos Plomp ee , Michael Magro ff, Paul W.G. Elbers gg , Yolande Appelman a , Niels van Royen a , r a Department of Cardiology, Amsterdam University Medical Center, location VUmc, Amsterdam, the Netherlands b Thorax Center, Erasmus Medical Center, Rotterdam, the Netherlands c Department of Epidemiology and Data Science, Amsterdam University Medical Center, location VUmc, Amsterdam, the Netherlands d Department of Cardiology, Amphia Hospital, Breda, the Netherlands e Department of Intensive care medicine, Amphia Hospital, Breda, the Netherlands f Department of Cardiology, Rijnstate Hospital, Arnhem, the Netherlands g Department of Intensive care medicine, Rijnstate Hospital, Arnhem, the Netherlands h Department of Cardiology, HAGA Hospital, Den Haag, the Netherlands i Department of Intensive care medicine, HAGA Hospital, Den Haag, the Netherlands j Department of Cardiology, Maasstad Hospital, Rotterdam, the Netherlands k Department of Intensive care medicine, Maasstad Hospital, Rotterdam, the Netherlands l University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, the Netherlands m University of Groningen, University Medical Center Groningen, Department of Intensive care medicine, Groningen, the Netherlands n Department of Cardiology, University Medical Center Utrecht, the Netherlands o Department of Intensive care medicine, University Medical Center Utrecht, the Netherlands p Department of Intensive care medicine, Medisch Spectrum Twente, Enschede, The Netherlands https://doi.org/10.1016/j.dib.2020.106521 2352-3409/© 2020 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license ( http://creativecommons.org/licenses/by-nc-nd/4.0/ ) 2 E.M. Spoormans, J.S. Lemkes and G.N. Janssens et al. / Data in Brief 33 (2020) 106521 q Department of Cardiology, Medisch Spectrum Twente, Enschede, The Netherlands r Department of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands s Department of Intensive care medicine, Radboud University Medical Center, Nijmegen, the Netherlands t Department of Cardiology, Amsterdam University Medical Center, location AMC, Amsterdam, the Netherlands u Department of Intensive care medicine, Amsterdam University Medical Center, location AMC, Amsterdam, the Netherlands v Department of Cardiology, OLVG, Amsterdam, the Netherlands w Department of Intensive care medicine, OLVG, Amsterdam, the Netherlands x Department of Cardiology, Noord West Ziekenhuisgroep, Alkmaar, the Netherlands y Department of Intensive care medicine, Noord West Ziekenhuisgroep, Alkmaar, the Netherlands z Department of Intensive care medicine, Maastricht University Medical Center, University Maastricht, Maastricht, the Netherlands aa Department of Cardiology, Maastricht University Medical Center, Maastricht, the Netherlands bb Department of Cardiology, Scheper Hospital, Emmen, the Netherlands cc Department of Cardiology, Haaglanden Medical Center, Den Haag, the Netherlands dd Department of Cardiology, Isala Hospital, Zwolle, the Netherlands ee Department of Cardiology, Tergooi Hospital, Blaricum, the Netherlands ff Department of Cardiology, Elisabeth-Tweesteden Hospital, Tilburg, the Netherlands gg Department of Intensive care medicine, Amsterdam University Medical Center, location VUmc, Amsterdam, the Netherlands a r t i c l e i n f o Article history: Received 27 October 2020 Accepted 9 November 2020 Available online 12 November 2020 Keywords: Sex differences Out-of-hospital cardiac arrest Coronary angiography One-year outcomes a b s t r a c t Sex differences in out-of-hospital cardiac arrest (OHCA) pa- tients are increasingly recognized. Although it has been found that post-resuscitated women are less likely to have significant coronary artery disease (CAD) than men, data on follow-up in these patients are limited. Data for this data in brief article was obtained as a part of the randomized controlled Coronary Angiography after Cardiac Arrest without ST-segment elevation (COACT) trial. The data supplements the manuscript “Sex differences in out-of-hospital cardiac ar- rest patients without ST-segment elevation: A COACT trial substudy” were it was found that women were less likely to have significant CAD including chronic total occlusions, and had worse survival when CAD was present. The dataset pre- sented in this paper describes sex differences on interven- tions, implantable-cardioverter defibrillator (ICD) shocks and hospitalizations due to heart failure during one-year follow- up in patients successfully resuscitated after OHCA. Data was derived through a telephone interview at one year with the patient or general practitioner. Patients in this randomized dataset reflects a homogenous study population, which can be valuable to further build on research regarding long-term sex differences and to further improve cardiac care. © 2020 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license ( http://creativecommons.org/licenses/by-nc-nd/4.0/ ) DOI of original article: 10.1016/j.resuscitation.2020.10.026 ∗ Corresponding author. E-mail address: j.lemkes@amsterdamumc.nl (J.S. Lemkes). E.M. Spoormans, J.S. Lemkes and G.N. Janssens et al. / Data in Brief 33 (2020) 106521 3 Specifications Table               Subject Clinical Cardiology Specific subject area Out-of-hospital cardiac arrest without ST-segment elevation; sex differences in out-of-hospital cardiac arrest; one-year outcomes after cardiac arrest Type of data Table How data were acquired Data was obtained from the randomized-controlled Coronary Angiography after Cardiac Arrest without ST-segment elevation (COACT) trial [1] . Data format Raw and analysed Parameters for data collection Patients successfully resuscitated from OHCA, without ST-segment elevation, were included in the trial in the time period from January 2015 until July 2018. All patients that survived until one-year follow-up were included in this data in brief article. Description of data collection In the open-label multicentre COACT trial, which was performed in 19 hospitals in the Netherlands, patients successfully resuscitated after cardiac arrest without ST-segment elevation on the first post-resuscitation electrocardiogram were assigned to undergo immediate coronary angiography or delayed coronary angiography strategy until after neurological recovery [1] . All coronary angiography and PCI procedures were evaluated at an independent core laboratory by personnel who were unaware of the treatment assignments [1] . Follow-up data were obtained by a telephone interview with the patient [2] . Data source location Amsterdam UMC – location VUMC De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands Data accessibility Data are within this article. Related research article Eva M. Spoormans, Jorrit S. Lemkes, Gladys N. Janssens, Nina W. van der Hoeven, Lucia S.D. Jewbali, Eric A. Dubois, Peter M. van de Ven, Martijn Meuwissen, Tom A. Rijpstra, Hans A. Bosker, Michiel J. Blans, Gabe B. Bleeker, Remon Baak, Georgios J. Vlachojannis, Bob J.W. Eikemans, Pim van der Harst, Iwan C.C. van der Horst, Michiel Voskuil, Joris J. van der Heijden, Albertus Beishuizen, Martin Stoel, Cyril Camaro, Hans van der Hoeven, José P. Henriques, Alexander P.J. Vlaar, Maarten A. Vink, Bas van den Bogaard, Ton A.C.M. Heestermans, Wouter de Ruijter, Thijs S.R. Delnoij, Harry J.G.M. Crijns, Gillian A.J. Jessurun, Pranobe V. Oemrawsingh, Marcel T.M. Gosselink, Koos Plomp, Michael Magro, Paul W.G. Elbers, Yolande Appelman, Niels van Royen. Sex differences in patients with out-of-hospital cardiac arrest without ST-segment elevation: A COACT trial substudy. In Press Value of the Data • Sex differences in OHCA patients are increasingly recognized. Although it has been found thatpost-resuscitated women are less likely to have significant CAD than men, data on follow-upin these patients are limited. This data in brief article provides sex disparities on interven-tions and hospitalizations during one-year follow-up. • All patients in this randomized dataset were successfully resuscitated after OHCA with aninitial shockable rhythm in absence of ST-segment elevation and therefore a reflects a ho-mogenous study population, which can be valuable to further build on research regardinglong-term sex differences. • The data provide insights on how sex differences in coronary angiography findings and initialtreatment strategy are related with long-term follow-up in men and women and can be usedto further improve personalized cardiac care. 1. Data Description Data was obtained as a part of the randomized controlled Coronary Angiography after Car-diac Arrest without ST-segment elevation (COACT) trial. This data in brief article contains infor-mation on long-term follow-up in men and women ( Table 1 ). Analysis was performed accordingto intention-to-treat principle. Events from discharge to one-year follow-up were calculated asnumbers and percentages of patients with odds ratios and 95% confidence intervals for dichoto-mous outcomes. Data was analyzed using IBM SPSS Statistics version 26 (IBM, Armonk, NewYork). 4 E.M. Spoormans, J.S. Lemkes and G.N. Janssens et al. / Data in Brief 33 (2020) 106521 Table 1 Interventions or hospitalization during one-year follow-up. Men ( N = 413) Women ( N = 109) Odds ratio 95% CI Coronary angiography — no. of patients. (%) 17/413 (4.1) 3/109 (2.8) 0.70 (0.19–2.29) Myocardial infarction — no. of patients. (%) 3/413 (0.7) 0/109 (0.0) a PCI — no. of patients. (%) 13/413 (3.1) 3/109 (2.8) 0.87 (0.24–3.11) CABG — no. of patients. (%) 3/413 (0.7) 1/109 (0.9) 1.27 (0.13–12.29) Hospitalization due to heart failure — no (%) 2/413 (0.5) 1/109 (0.9) 1.9 (0.17–21.18) ICD implantation — no. of patients. (%) 11/413 (2.7) 1/109 (0.9) 0.34 (0.04–2.64) ICD shocks — no. of patients. (%) 31/413 (7.5) 9/109 (8.3) 1.11 (0.51–2.41) Appropriate ICD shocks — no. of patients. (%) 27/413 (6.5) 4/109 (3.7) 0.12 (0.02–0.64) Composite of death, revascularization or myocardial infarction after index hospitalization — no. of patients. (%) 168/413 (40.7) 48/109 (44.0) 1.15 (0.75–1.76) All data are expressed in numbers and percentages (%). a OR and 95% not determined because of absence of events in women . PCI denotes percutaneous coronary interven- tion, CABG coronary artery bypass graft, ICD implantable cardioverter-defibrillator. 2 b  a  p  c  t  t  r  f  g  t  5 n  d  t  v  c  pE wD a  a  b  w. Experimental Design, Materials and Methods The investigator initiated, multicenter randomized controlled COACT trial investigated theenefit of immediate coronary angiography in patients successfully resuscitated after cardiacrrest without ST-segment elevation on the first post-resuscitation electrocardiogram [1] . Im-ortant exclusion criteria were signs of ST-segment elevation, shock or an obvious non-coronaryause [1] . Further in- and exclusion criteria were reported previously [3] . Eligible patients forhe study were randomized in a 1:1 ratio to either immediate coronary angiography (i.e. withinwo hours after randomization) or delayed coronary angiography strategy until after neurologicalecovery. In 19 participating hospitals in the Netherlands, a total of 552 patients were enrolledrom January 2015 until July 2018. Post-resuscitation care was according to the resuscitationuidelines [4] . Fourteen patients retroactively withdrew informed consent. In addition, 13 pa-ients refused consent for the one-year follow-up and 3 patients were lost to follow-up. In total,22 patients had data available for assessment at one year [2] . Data for the one-year follow-up included patients of whom follow-up was obtained and didot retract informed consent [2] . Death registries were searched to registry deaths. Follow-upata on interventions such as death, myocardial infarction, invasive coronary angiography or in-erventions, hospitalizations or implantable cardioverter defibrillator (ICD) therapy was obtainedia an telephone interview with the patient, a family member or via patients’ the general physi-ian [2] . Information was obtained by members of the research team who were blinded for theatient’s treatment allocation. thics Statement Deferred informed consent was obtained from all patients that were enrolled in the studyith the use of a prespecified procedure [1] . eclaration of Competing Interest Supported by unrestricted research grants from the Netherlands Heart Institute, Biotronik,nd AstraZeneca. Dr. Vlachojannis reports receiving grant support from MicroPort Orthopedicsnd Daiichi Sankyo; and Dr. van Royen, receiving grant support from Philips, Biotronik, and Ab-ott and honoraria from Medtronic. No other potential conflict of interest relevant to this articleas reported. E.M. Spoormans, J.S. Lemkes and G.N. Janssens et al. / Data in Brief 33 (2020) 106521 5        Supplementary Materials Supplementary material associated with this article can be found in the online version atdoi: 10.1016/j.dib.2020.106521 . References [1] JS Lemkes , GN Janssens , NW van der Hoeven , LSD Jewbali , EA Dubois , M Meuwissen , et al. , Coronary angiographyafter cardiac arrest without ST-segment elevation, N. Engl. J. Med. 380 (15) (2019) 1397–1407 . [2] JS Lemkes , GN Janssens , NW van der Hoeven , LSD Jewbali , EA Dubois , MM Meuwissen , et al. , Coronary angiographyafter cardiac arrest without ST segment elevation: one-year outcomes of the COACT randomized clinical trial, JAMACardiol. (2020) . [3] JS Lemkes , GN Janssens , HM Straaten , PW Elbers , NW van der Hoeven , JG Tijssen , et al. , Coronary angiography aftercardiac arrest: rationale and design of the COACT trial, Am. Heart J. 180 (2016) 39–45 . [4] JP Nolan , J Soar , A Cariou , T Cronberg , VR Moulaert , CD Deakin , et al. , European resuscitation council and Europeansociety of intensive care medicine 2015 guidelines for post-resuscitation care, Intensive Care Med. 41 (12) (2015)2039–2056 . 

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Data on sex differences in one-year outcomes of out-of-hospital cardiac arrest patients without ST-segment elevation

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