Considering the future trends of biomaterials, current studies are focused on the corrosion
resistance and the mechanical properties of new materials that need to be considered in the
process of strengthening alloys with additive non-toxic elements. Many kinds of titanium alloys with
different biocompatible elements (Mo, Si, Zr, etc.,) have been recently developed for their similar
properties with human bone. Four new different alloys were obtained and investigated regarding
their microstructure, mechanical, chemical, and biological behavior (in vitro and in vivo evaluation),
the alloys are as follows: Ti15Mo7Zr15Ta, Ti15Mo7Zr15Ta0.5Si, Ti15Mo7Zr15Ta0.75Si, and
Ti15Mo7Zr15Ta1Si. There were changes with the addition of the silicon element such as the hardness
and the modulus of elasticity increased. An MTT assay confirmed the in vitro cytocompatibility of
the prepared alloys