Anetoderma is characterized by a loss of normal elastic tissue that presents
clinically as localized areas of wrinkled or flaccid skin. We describe the case
of a 30-year-old woman with systemic lupus erythematosus-associated anetoderma
and positive anti-phospholipid antibodies. We discuss the possible role of these
antibodies in the pathogenesis of anetoderma, and, when detected, the need to
check for an associated anti-phospholipid syndrome in such patients
