Epigenetic Signatures Associated with Different Levels of Differentiation Potential in Human Stem Cells

Agirre-Ena, X. (Xabier); Andreu, E.J. (Enrique José); Aranda, P. (P.); Ballestar, E. (E.); Cigudosa, J.C. (Juan Cruz); Esteller, M. (Manel); Martin-Subero, J.I. (Jose Ignacio); Prieto, I. (Inés); Prosper, F. (Felipe); Roman-Gomez, J. (José); Siebert, R. (Reiner)

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Epigenetic Signatures Associated with Different Levels of Differentiation Potential in Human Stem Cells

Authors: X. (Xabier) Agirre-Ena
E.J. (Enrique José) Andreu
P. (P.) Aranda
E. (E.) Ballestar
J.C. (Juan Cruz) Cigudosa
M. (Manel) Esteller
J.I. (Jose Ignacio) Martin-Subero
I. (Inés) Prieto
F. (Felipe) Prosper
J. (José) Roman-Gomez
R. (Reiner) Siebert
Publication date: 1 January 2009
Publisher: 'Public Library of Science (PLoS)'

Abstract

The therapeutic use of multipotent stem cells depends on their differentiation potential, which has been shown to be variable for different populations. These differences are likely to be the result of key changes in their epigenetic profiles

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