Our laboratory is interested in understanding the role of Type II alpha 1 collagen (Col2a1) in vertebrate development. We utilize Danio rerio, the common zebrafish, to elucidate the function of the zebrafish version of this gene. Our goal is to visualize and locate the presence of the type II alpha 1 collagen b gene (col2a1b) in zebrafish. col2a1b\u27s collagen expression occurs solely in the perichondrium, while its paralog, col2a1a, is expressed in chondrocytes and in the perichondrium. A goal of our project is to discover how the col2a1b gene maintains its expression in the perichondrium using in situ hybridization
