The development of regional metamorphism in areas of thickened continental crust is investigated in terms of the major controls on regional-scale thermal regimes. These are: the total radiogenic heat supply within the thickened crust, the supply of heat from the mantle, the thermal conductivity of the medium and the length and time scales of erosion of the continental crust. The orogenic episode is regarded as consisting of a relatively rapid phase of crustal thickening, during which little temperature change occurs in individual rocks, followed by a lengthier phase of erosion, at the end of which the crust is at its original thickness. The principal features of pressure—temperature—time (PTt) paths followed by rocks in this environment are a period of thermal relaxation, during which the temperature rises towards the higher geotherm that would be supported by the thickened crust, followed by a period of cooling as the rock approaches the cold land surface. The temperature increase that occurs is governed by the degree of thickening of the crust, its conductivity and the time that elapses before the rock is exhumed sufficiently to be affected by the proximity of the cold upper boundary. For much of the parameter range considered, the heating phase encompasses a considerable portion of the exhumation (decompression) part of the PTt path. In addition to the detailed calculation of PTt paths we present an idealized model of the thickening and exhumation process, which may be used to make simple calculations of the amount of heating to be expected during a given thickening and exhumation episode and of the depth at which a rock will start to cool on its ascent path. An important feature of these PTt paths is that most of them lie within 50 °C of the maximum temperature attained for one third or more of the total duration of their burial and uplift, and for a geologically plausible range of erosion rates the rocks do not begin to cool until they have completed 20 to 40 per cent of the total uplift they experience. Considerable melting of the continental crust is a likely consequence of thickening of crust with an average continental geotherm. A companion paper discusses these results in the context of attempts to use metamorphic petrology data to give information on tectonic processe