Discrete Event Simulation (DES) has become a useful tool in the evaluation of changes that may bring positivity to manufacturing and process organizations for both goods and services provision. The main focus of any business entails the reduction of cost and lead time while increasing profits and this is why refining of production processes is essential. This paper reports the application of DES in two case studies. The case studies selected for the implementation of Discrete Event Simulation are a packaging company and a local mobile phone service provider using the software FlexSim. The implementation aims at showcasing the versatility and its ability to provide the relevant data to make more informed decision while optimizing the entire processes involved in production