Early Detection of Parkinson's Disease using Motor Symptoms and Machine Learning

Abstract

Parkinson's disease (PD) has been found to affect 1 out of every 1000 people, being more inclined towards the population above 60 years. Leveraging wearable-systems to find accurate biomarkers for diagnosis has become the need of the hour, especially for a neurodegenerative condition like Parkinson's. This work aims at focusing on early-occurring, common symptoms, such as motor and gait related parameters to arrive at a quantitative analysis on the feasibility of an economical and a robust wearable device. A subset of the Parkinson's Progression Markers Initiative (PPMI), PPMI Gait dataset has been utilised for feature-selection after a thorough analysis with various Machine Learning algorithms. Identified influential features has then been used to test real-time data for early detection of Parkinson Syndrome, with a model accuracy of 91.9