Additional file 1: Fig. S1. Implementation of hADAR2 editing system in S. pombe. Fig. S2. Confirmation of candidate A-to-I RNA editing sites by sanger sequencing. Fig. S3. Base-calling errors can be used to identify I-type reads in direct Nanopore reads. Fig. S4. Performance of models with different feature selection. Fig. S5. Challenge of reads mapping in repetitive elements by the short-read sequencing. Fig. S6. Changes in potential hydrogen bond interactions between bases induced by A-to-I RNA editing events in transcript NM_002794.5