Antimicrobial hydrogels, both in semi-stiff sheets and amorphous form, have been extensively
studied for wound management mainly owing to their high-water content, lower wound
adherence, promoted autolysis debridement, epithelial migration, and granulation growth.
Benefiting from the recent advances in materials science, biotechnology, and a growing
understanding of wound microbiology, an extensive variety of antimicrobial hydrogels have
been developed. These novel antimicrobial hydrogels can prevent and control microbial
infection. In addition, they possess wound healing functions for improved wound management.
This chapter will provide a comprehensive summary of the current studied antimicrobial
hydrogels in literature and available hydrogel dressings in the market, including their design,
fabrication method, and wound management efficacy in vitro or in vivo. The detailed and
critical discussion of the advantages and disadvantages of each type of hydrogel dressing will
provide insights into the future design of antimicrobial hydrogels for better management of
wounds in clinical application
