Diabetes Mellitus is a metabolic disorder that is growing at epidemic proportions worldwide and is consensually classified in type 1 Diabetes, type 2 Diabetes and Gestational Diabetes. One of the most common complication of diabetes is the lower extremity is the diabetic foot ulcer (DFU). Diabetes is also the most common cause of lower extremity amputation (LEA). Several foot disorders, such as foot ulcerations and infections are a major source of morbidity and a leading cause of hospitalization for persons with diabetes. Thus, ulceration, infection, gangrene, and limb amputation are major complications of the disease, estimated to cost billions of dollars each year and have attracted the attention of health policy providers.info:eu-repo/semantics/publishedVersio
