Basu, Arun

Das, Sukta

Mitra, Amar

Mitra, Santosh

The serum lysozyme concentrations were determined in the host mice bearing a transplantable ascitic lymphoma during growth of the tumour. Simultaneously, the hematological changes were also recorded. These ob-servations were made at weekly intervals till the animals survived and were made at weekly intervals till the animals survived and were compared with their normal counterparts. It has been shown that there is a progressive increase in the concentration of lysozyme along with the growth of the tumour cells within the peritoneal cavity which reaches a peak on the third week following transplantation of tumour cells and then falls off. The con-centration of the enzyme, however, never reaches the normal values ob-served. This shows a parallelism with the growth pattern of the tumour in general. Total and differential counts of white blood cells revealed a marked rise in the total leukocyte counts and a reversal of the lymphoid-myeloid ratio during the growth of the tumour in the host

Serum Lysozyme Pattern and Hematological Changes in the Host During Growth of a Transplantable Murine Lymphoma

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