α-Lipoic Acid Ameliorates The Changes in Prooxidant-Antioxidant Balance in Liver and Brain Tissues of Propylthiouracil-Induced Hypothyroid Rats.

Abstract

Objective: There are controversial data about the prooxidant-antioxidant balance in hypothyroidism. We aimed to investigate the effect of alpha-lipoic acid (ALA) on oxidative stress parameters in the liver and brain of propylthiouracil (PTU)-induced hypothyroid rats