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Coment on : The maximum effective needle-to-nerve distance for ultrasound-guided interscalene block: an exploratory study. [Reg Anesth Pain Med. 2014]]]> interscalene block; patient eng oai:serval.unil.ch:BIB_7C5BB1A51EF1 2022-05-07T01:21:10Z phdthesis urnserval <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_7C5BB1A51EF1 Etude radiologique des lésions du parenchyme rénal chez 50 enfants atteints d'infection urinaire récidivante Godat, Pierre-Michel Université de Lausanne, Faculté de médecine info:eu-repo/semantics/doctoralThesis phdthesis 1978 fre https://serval.unil.ch/resource/serval:BIB_7C5BB1A51EF1.P001/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_7C5BB1A51EF19 info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_7C5BB1A51EF19 info:eu-repo/semantics/restrictedAccess Restricted: indefinite embargo Copying allowed only for non-profit organizations https://serval.unil.ch/disclaimer application/pdf oai:serval.unil.ch:BIB_7C5D453F3147 2022-05-07T01:21:10Z <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_7C5D453F3147 HLA and HIV: modeling adaptation to moving targets. info:doi:10.1038/sj.tpj.6500200 info:eu-repo/semantics/altIdentifier/doi/10.1038/sj.tpj.6500200 info:eu-repo/semantics/altIdentifier/pmid/14583794 Telenti, A. Beckmann, J.S. Mallal, S. info:eu-repo/semantics/article article 2003 The pharmacogenomics journal, vol. 3, no. 5, pp. 254-256 info:eu-repo/semantics/altIdentifier/pissn/1470-269X urn:issn:1470-269X Animals; Gene Targeting/methods; HIV/genetics; HLA Antigens/genetics; Humans eng oai:serval.unil.ch:BIB_7C5D5BD8F500 2022-05-07T01:21:10Z openaire documents urnserval <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_7C5D5BD8F500 Overexpressed or intraperitoneally injected human transferrin prevents photoreceptor degeneration in rd10 mice. info:eu-repo/semantics/altIdentifier/pmid/21179240 Picard, E. Jonet, L. Sergeant, C. Vesvres, M.H. Behar-Cohen, F. Courtois, Y. Jeanny, J.C. info:eu-repo/semantics/article article 2010 Molecular Vision, vol. 16, pp. 2612-2625 info:eu-repo/semantics/altIdentifier/eissn/1090-0535 urn:issn:1090-0535 <![CDATA[PURPOSE: Retinal degeneration has been associated with iron accumulation in age-related macular degeneration (AMD), and in several rodent models that had one or several iron regulating protein impairments. We investigated the iron concentration and the protective role of human transferrin (hTf) in rd10 mice, a model of retinal degeneration. METHODS: The proton-induced X-ray emission (PIXE) method was used to quantify iron in rd10 mice 2, 3, and 4 weeks after birth. We generated mice with the β-phosphodiesterase mutation and hTf expression by crossbreeding rd10 mice with TghTf mice (rd10/hTf mice). The photoreceptor loss and apoptosis were evaluated by terminal deoxynucleotidyl transferase dUTP nick end labeling in 3-week-old rd10/hTf mice and compared with 3-week-old rd10 mice. The neuroprotective effect of hTf was analyzed in 5-day-old rd10 mice treated by intraperitoneal administration with hTf for up to 25 days. The retinal hTf concentrations and the thickness of the outer nuclear layer were quantified in all treated mice at 25 days postnatally. RESULTS: PIXE analysis demonstrated an age-dependent iron accumulation in the photoreceptors of rd10 mice. The rd10/hTf mice had the rd10 mutation, expressed high levels of hTf, and showed a significant decrease in photoreceptor death. In addition, rd10 mice intraperitoneally treated with hTf resulted in the retinal presence of hTf and a dose-dependent reduction in photoreceptor degeneration. CONCLUSIONS: Our results suggest that iron accumulation in the retinas of rd10 mutant mice is associated with photoreceptor degeneration. For the first time, the enhanced survival of cones and rods in the retina of this model has been demonstrated through overexpression or systemic administration of hTf. This study highlights the therapeutic potential of Tf to inhibit iron-induced photoreceptor cell death observed in degenerative diseases such as retinitis pigmentosa and age-related macular degeneration