The aim of this paper is to study the design of isotropic composites reinforced by aligned spheroidal particles made of a transversely isotropic material. The problem is investigated analytically using the framework of mean- eld homogenization. Conditions of macroscopic isotropy of particle-reinforced composites are derived for the dilute and Mori-Tanaka's schemes. This leads to a system of three nonlinear equations linking seven material constants and two geometrical constants. A design tool is finally proposed which permits to determine admissible particles achieving macroscopic isotropy for a given isotropic matrix behavior and a given particle aspect ratio. Correlations between transverse and longitudinal moduli of admissible particles are stud- ied for various particle shapes. Finally, the design of particles is investigated for aluminum and steel matrix composites