All melanoma suspected patients must be confirmed histologically and resected. Sentinel node biopsy
must be done when tumor is over 1 mm or if less with
high-risk factors. Adjuvant therapy with interferon could
be offered for patients with high-risk melanoma and in
selected cases radiotherapy can be added. Metastatic melanoma treatment is guided by mutational BRAF status.
BRAF wild type patients must receive anti-PD1 containing
therapy and BRAF mutated patients BRAF/MEK inhibitors
or anti-PD1 containing therapy. Up to 10 years follow up is
reasonable for melanoma patients with dermatologic
examinations and physical exams