Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2019, Tutors: Raúl Tudela, Roser Sala LlonchAlzheimer's Disease (AD) is a progressive age-related neurodegenerative disorder, which can be studied through the use of transgenic animal models. AD is characterized by a loss of brain gray matter, resulting in changes in the cortical thickness that can be measured from Magnetic Resonance Imaging (MRI). The present work aimed to measure the cortical thickness from rat brain MRI by creating an automated tailored program implemented in Python and using available algorithms and in-house designed functions. The program was further used to analyse the temporal evolution of the cortical thickness in a transgenic AD model compared to control wild-type rat
