Nanoparticles have surprised the mankind ever since their dawn. The uniqueness in their properties compelled the scientific community to adopt different synthetic approaches. Though each synthetic route has its own importance yet among them green synthetic method is preferred over the others because of its costeffectiveness, eco-friendliness. We also synthesized the zinc oxide nanoparticles through green synthetic method. Zinc oxide nanoparticles prepared using Lagerstroemia Specio leaves were characterized by Ultraviolet-visible spectrophotometry, Dynamic Light Scattering, Fourier Transformer-infrared, Scanning Electron Microscopy, X-ray Diffraction for size, shape and nature. The so-prepared zinc oxide nanoparticles were studied for their various activities i.e. antioxidant activity, Catalytic activity, anti-diabetic activity, anti-microbial activity