Nitrofurantoin: Furious Against Bacteria? an in Vitro Study to Test Nitrofurantoin as an Intracanal Medicament Against Enterococcus Faecalis

Abstract

In vitro evaluation of nitrofurantoin as an intracanal medicament against Enterococcus Faecalis. Materials and Methods: 150 single-rooted premolar teeth were chosen and instrumented using a Protaper gold rotary file system; the root canals of these teeth were inoculated for 21 days with an Enterococcus faecalis bacterial solution. The canals were inoculated with Nitrofurantoin, Calcium hydroxide, and MTAP after 21 days and left for 7 days. On the eighth day, the samples were examined to determine the degree of infection. The study's findings revealed that both Nitrofurantoin and MTAP were very successful, with no Colony Forming Units (CFU) production in their respective groups. The current investigation indicated that nitrofurantoin is effective in eradicating E. faecalis cells in pure culture as well as root canals