In vitro measurements are widely used to implement gait kinematic and
kinetic parameters to predict THA wear rate. Clinical tests of materials
and designs are crucial to prove the accuracy and validate such
measurements. This research aimed to examine the effect of CoC and
CoXLPE kinematics and kinetics on wear during gait, the essential
functional activity of humans, by comparing in vivo data to in vitro
results. Our study hypothesis was that both implants would present the
same hip joint kinematics and kinetics during gait. In total, 127
unilateral primary cementless total hip arthroplasties were included in
the research. There were no statistically significant differences
observed at mean peak abduction, flexion, and extension moments and THA
kinematics between the two groups. THA gait kinematics and kinetics are
crucial biomechanical inputs associated with implant wear. In vitro
studies report less wear in CoC than CoXLPE when tested in a matched
gait kinematic protocol. Our findings confirm that both implants behave
identically in terms of kinematics in a clinical environment, thus
strengthening CoC advantage in in vitro results. Correlated to all other
significant factors that affect THA wear, it could address in a complete
prism the wear on CoC and CoXLPE