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Primary angiosarcoma of the kidney: Literature review of a rare nosologic entity
Authors
A. Mastoraki Schizas, D. Giannakas, T. Papadopoulos, P.P. Naar, L. Vergadis, C. Anastasiou, I. Vassiliu, P. Pikoulis, E. Liakakos, T.
Publication date
1 January 2020
Publisher
Abstract
Primary angiosarcoma of the kidney is a rare tumor, hence little is known concerning its diagnostic features and therapeutic management. We conducted this survey to present a complete literature review with emphasis on clinicopathological features, diagnosis and therapy. A thorough search was conducted in MEDLINE/PubMed. All relevant studies concerning primary renal angiosarcomas in adults were thoroughly reviewed. Primary renal angiosarcoma is characterized by an overall poor prognosis, is of unknown etiology and occurs most commonly in males between 60 and 70 years old. Presence of distant metastasis at the time of diagnosis is prevalent. Histopathological examination and immunohistochemical studies are the most important diagnostic tools. Treatment options include surgery, chemotherapy, radiotherapy and immunotherapy. Conclusion: Primary renal angiosarcoma is a rare but aggressive malignancy with low response to available therapeutic regimens and dismal survival rates. © 2020 International Institute of Anticancer Research. All rights reserved
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Pergamos : Unified Institutional Repository / Digital Library Platform of the National and Kapodistrian University of Athens
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Last time updated on 10/02/2023