Matrix-producing carcinoma (MPC) is a rare subtype of metaplastic breast
carcinoma (MBC) that was first described in 1989 by Wargotz and Norris.
It accounts for less than 1% of breast carcinomas and has distinctive
clinical, morphological, and immunohistochemical features.
Histologically it consists of invasive carcinoma of no special type with
transition to cartilaginous or osseous matrix without a spindle cell
component. Data on this entity are limited with the literature
consisting mostly of case reports and a small number of case series.
We report a case of matrix-producing breast carcinoma, with excellent
clinical outcome. We also discuss the histogenesis, imaging,
histological, and immunohistochemical characteristics, treatment, and
focus on the differential diagnosis of this rare tumor
