In this work we propose a simple method to obtain groups of homologous genes across multiple
(k) organisms, called kGC. Our method takes as input all-against-all Blastp comparisons and produces groups
of homologous sequences. First, homologies among groups of paralogs of all the k compared genomes are
found, followed by homologies of groups among k - 1 genomes and so on, until groups belonging exclusively
to only one genome, that is, groups of one genome not presenting strong similarities with any group of
any other genome, are identified. We have used our method to determine homologous groups across six
Actinobacterial complete genomes. To validate kGC, we first investigate the Pfam classification of the homologous groups, and after compare our results with those produced by OrthoMCL. Although kGC is much
simpler than OrthoMCL it presented similar results with respect to Pfam classification