Data Set and Methods for Association of Angiotensin Receptor Autoantibodies with Abnormal Cardiovascular Abnormalities in Preeclampsia

Abstract

This dataset is associated with an article entitled "Association of Angiotensin Receptor Autoantibodies with Cardiovascular Abnormalities in Preeclampsia." The text describes a study of a prospective cohort of women with preeclampsia with severe features of preeclampsia and controls. Twenty-one women with prior preeclampsia and twenty normotensive controls underwent evaluation at recruitment and at 4-year follow-up. A subset of 12 women with preeclampsia and 12 controls underwent echocardiography and had their serum levels of an angiotensin II type I receptor autoantibody measured by a quantitative antigen capture immunoassay at the same time. A subset of 12 women with preeclampsia and 12 controls underwent echocardiography 4 years postpartum and were similarly evaluated. The associations between the autoantibody levels and demographics, echocardiographic indices of diastolic dysfunction and with incident hypertension were determined