Cheng, S

Gruendig, B

Kaptein, WA

Korf, J

Renneberg, R

Yuen, Y

A simple portable continuous L-lactate monitoring system combining elegant ultrafiltration sample collection and storage with a lactate biosensor has been developed. The sensor has a detection range from 0.05mM to 30mM lactate dependent on different assignments of the PCS hydrogel complex layer. The sensor shows excellent performance on sensitivity and validity as well as operational stability over one month. Samples containing different concentrations of lactate were collected in six hours with an ultrafiltration probe and stored in a 6m long PEEK tube of 125 mu m in internal diameter. The ultraslow flow rate of 100 to 350nl/min was controlled by adjusting the restriction in the portable plastic syringe pump and a constant flow can be maintained over 24 hours. The collected samples were then detected after reversing the now with a lactate sensor. The total weight of the collection system is only 8g, allowing free movement of the person being tested.</p

Continuous lactate measurement that combines a portable ultrafiltration storage device with an enzyme sensor

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