Moorlag, Hendrik

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Dit proefschrift handelt over nieuwe syntheseroutes voor enantiomeer zuivere α-gesubstitueerde α-hydroxyzuren. Deze verbindingen zijn belangrijke synthetische intermediairen in de stereoselektieve synthese. Tot dusver zijn optisch aktieve α-gesubstitueerde α-hydroxyzuren gesynthetiseerd gebruik makend van tamelijk bewerkelijke syntheses. De toegang tot deze verbindingen in enantiomeer zuivere vorm is beperkt aangezien een algemene stereoselektieve route niet beschikbaar is. Het doel van het in dit proefschrift beschreven onderzoek is om een algemene katalytische stereoselektieve synthese van α-gesubstitueerde α-hydroxymren te ontwikkelen. Dit kan verder onderzoek naar de synthetische mogelijkheden van deze chirale bouwstenen mogelijk maken

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   University of GroningenChiral α-substituted α-hydroxy acidsMoorlag, HendrikIMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite fromit. Please check the document version below.Document VersionPublisher's PDF, also known as Version of recordPublication date:1991Link to publication in University of Groningen/UMCG research databaseCitation for published version (APA):Moorlag, H. (1991). Chiral α-substituted α-hydroxy acids: (stereoselective) synthesis using transition metaland enzyme catalysis. s.n.CopyrightOther than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of theauthor(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).The publication may also be distributed here under the terms of Article 25fa of the Dutch Copyright Act, indicated by the “Taverne” license.More information can be found on the University of Groningen website: https://www.rug.nl/library/open-access/self-archiving-pure/taverne-amendment.Take-down policyIf you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediatelyand investigate your claim.Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons thenumber of authors shown on this cover page is limited to 10 maximum.Download date: 13-02-2023

Chiral α-substituted α-hydroxy acids:(stereoselective) synthesis using transition metal and enzyme catalysis

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Chiral α-substituted α-hydroxy acids:(stereoselective) synthesis using transition metal and enzyme catalysis

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